What is the catalog number for BI-1622?

The catalog number for BI-1622 is T63492.

What sizes are available for BI-1622?

BI-1622 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does BI-1622 come in?

BI-1622 is available in 3 different pack sizes.

BI-1622 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BI-1622?

BI-1622 is manufactured by Molfinity.

What is the estimated delivery time for BI-1622?

Estimated delivery time for BI-1622 is approximately 10 business day(s), depending on your location.

BI-1622

Product Specifications

CAS Number

2681392-19-6

Target

Others, BTK, PI4K, JAK, EGFR, Raf, CDK, Tyrosine Kinases

Related Pathways

Chromatin/Epigenetic, JAK/STAT signaling, MAPK, Stem Cells, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Others, Angiogenesis

Bioactivity

BI-1622 is a highly selective, orally active HER2 (ERBB2) inhibitor (IC50: 7 nM) . BI-1622 is >25-fold selective for EGFR. In a mouse model of transplanted tumors transfected with H2170 and PC9 cells, BI-1622 exhibited high in vivo antitumor effects with good drug metabolism and pharmacokinetic properties.