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CDK9-IN-19

Product Specifications

CAS Number

2479306-60-8

Target

Others, CDK

Related Pathways

Others, Cell Cycle/Checkpoint

Bioactivity

CDK9-IN-19 is a selective and potent CDK9 inhibitor (IC50: 2.0 nM) . CDK9-IN-19 exhibits good anti-proliferative activity in cancer cells, moderate pharmacokinetic properties and low hERG inhibition. CDK9-IN-19 significantly inhibited tumor growth in the MV4-11 xenograft mouse model. CDK9-IN-19 can be used in studies of acute myeloid leukemia (AML) .

Smiles

C(C)(=O)C1=C(C=2C(=CC(NC=3N=C(C(F)=CN3)C4=C(OC)C=C(F)C=C4)=CC2)OC1=O)N5CCOCC5

Molecular Formula

C26H22F2N4O5

Molecular Weight

508.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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