CDK9-IN-19
Product Specifications
CAS Number
2479306-60-8
Target
Others|||CDK
Related Pathways
Others|||Cell Cycle/Checkpoint
Bioactivity
CDK9-IN-19 is a selective and potent CDK9 inhibitor (IC50: 2.0 nM) . CDK9-IN-19 exhibits good anti-proliferative activity in cancer cells, moderate pharmacokinetic properties and low hERG inhibition. CDK9-IN-19 significantly inhibited tumor growth in the MV4-11 xenograft mouse model. CDK9-IN-19 can be used in studies of acute myeloid leukemia (AML) .
Smiles
C(C)(=O)C1=C(C=2C(=CC(NC=3N=C(C(F)=CN3)C4=C(OC)C=C(F)C=C4)=CC2)OC1=O)N5CCOCC5
Molecular Formula
C26H22F2N4O5
Molecular Weight
508.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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