PI3Kα-IN-8
Product Specifications
Target
Others, Apoptosis, Reactive Oxygen Species, PI3K
Related Pathways
NF-κB, Others, PI3K/Akt/mTOR signaling, Immunology/Inflammation, Apoptosis, Metabolism
Bioactivity
PI3Kα-IN-8 is a selective inhibitor of PI3Kα (IC50: 0.012 μM) . PI3Kα-IN-8 increases intracellular levels of reactive oxygen species, decreases mitochondrial membrane potential, and induces apoptosis.
Molecular Formula
C26H27BrN4O2
Molecular Weight
507.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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