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PI3Kα-IN-8

Product Specifications

Target

Others, Apoptosis, Reactive Oxygen Species, PI3K

Related Pathways

NF-κB, Others, PI3K/Akt/mTOR signaling, Immunology/Inflammation, Apoptosis, Metabolism

Bioactivity

PI3Kα-IN-8 is a selective inhibitor of PI3Kα (IC50: 0.012 μM) . PI3Kα-IN-8 increases intracellular levels of reactive oxygen species, decreases mitochondrial membrane potential, and induces apoptosis.

Molecular Formula

C26H27BrN4O2

Molecular Weight

507.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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