PARP1/BRD4-IN-1
Product Specifications
CAS Number
2758117-74-5
Target
Apoptosis|||PARP|||Epigenetic Reader Domain|||Others|||DNA/RNA Synthesis
Related Pathways
Apoptosis|||Others|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Bioactivity
PARP1/BRD4-IN-1 is a highly selective and potent inhibitor of PARP1 (IC50: 49 nM) and BRD4 (IC50: 202 nM), which inhibits the expression and activity of PARP1 and BRD4, thereby synergistically suppressing the malignant growth of pancreatic cancer cells.
Smiles
C(N1C(C=2C(N(C)C1=O)=CC=C(C2)C=3C(C)=NOC3C)C4=CC=CC=C4)C=5NC=6C(N5)=CC=CC6C(N)=O
Molecular Formula
C29H26N6O3
Molecular Weight
506.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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