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PI3K/mTOR Inhibitor-8

Product Specifications

CAS Number

2492376-85-7

Target

MTOR, Others, PI3K

Related Pathways

PI3K/Akt/mTOR signaling, Others

Bioactivity

PI3K/mTOR Inhibitor-8 is a dual inhibitor of PI3K (PI3Kα IC50: 0.46 nM) and mTOR (mTOR IC50: 12 nM) . PI3K/mTOR Inhibitor-8 blocks the cell cycle of HCT-116 cells in G1/S phase and induces apoptosis. apoptosis) .

Smiles

C(NNC(=O)C1=CC=C(OC)C=C1)(=O)C=2SC3=C(N=C(N=C3C2)C=4C=NC(N)=NC4)N5CCOCC5

Molecular Formula

C23H22N8O4S

Molecular Weight

506.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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