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WYE-132

Product Specifications

CAS Number

1144068-46-1

Target

Apoptosis, mTOR

Related Pathways

PI3K/Akt/mTOR signaling, Apoptosis

Purity

0.9916

Bioactivity

WYE-125132 (WYE-132 (WYE-125132) ) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.

Smiles

CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCC4(CC3)OCCO4)c2n1

Molecular Formula

C27H33N7O4

Molecular Weight

519.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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