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PKRA83

Product Specifications

CAS Number

1233926-87-8

Target

Others

Related Pathways

Others

Bioactivity

PKRA83 is a potent prokineticin (PK2) antagonist that crosses the blood-brain barrier and competes for PK2 binding to its receptors PKR1 and PKR2. PKRA83 effectively inhibits PK2 receptors and acts on PKR1 (IC50: 5.0 nM) and PKR2 (IC50: 8.2 nM) . PKRA83 exhibits anti-cancer and anti-angiogenic effects.

Smiles

ClC1=C2C(=CC(CN(C(=O)[C@H]3CN(CC4=CC(OC)=C(F)C=C4)CC3)CC(C)C)=C1)OCCCO2

Molecular Formula

C27H34ClFN2O4

Molecular Weight

505.02

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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