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HDAC-IN-45

Product Specifications

CAS Number

2421122-61-2

Target

Others, HDAC

Related Pathways

Others, DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

HDAC-IN -45, a small molecule HDAC inhibitor, was able to form hydrogen bonds with Y303 residues and exhibited anticancer effects. HDAC-IN-45 significantly inhibited HDAC1, HDAC2 and HDAC3 subtypes with their IC50 values of 0.108, 0.585 and 0.563 μM, respectively.

Smiles

C(N1C=2C(=C(NC3=CC(Cl)=C(F)C=C3)N=C(N)N2)N=C1)C4=CC=C(C(NC5=C(N)C=CC=C5)=O)C=C4

Molecular Formula

C25H20ClFN8O

Molecular Weight

502.93

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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