HDAC-IN-45
Product Specifications
CAS Number
2421122-61-2
Target
Others|||HDAC
Related Pathways
Others|||DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
HDAC-IN -45, a small molecule HDAC inhibitor, was able to form hydrogen bonds with Y303 residues and exhibited anticancer effects. HDAC-IN-45 significantly inhibited HDAC1, HDAC2 and HDAC3 subtypes with their IC50 values of 0.108, 0.585 and 0.563 ?M, respectively.
Smiles
C(N1C=2C(=C(NC3=CC(Cl)=C(F)C=C3)N=C(N)N2)N=C1)C4=CC=C(C(NC5=C(N)C=CC=C5)=O)C=C4
Molecular Formula
C25H20ClFN8O
Molecular Weight
502.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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