HDAC-IN-39
Product Specifications
CAS Number
2414046-33-4
Target
HDAC, Microtubule Associated, Others, Apoptosis
Related Pathways
Chromatin/Epigenetic, Others, DNA Damage/DNA Repair, Cytoskeletal Signaling, Apoptosis
Bioactivity
HDAC-IN-39 is a potent inhibitor of HDAC and is able to act on HDAC1, HDAC2 and HDAC3 with IC50 values of 1.07 μM, 1.47 μM and 2.27 μM, respectively. HDAC-IN-39 induces cell cycle arrest in G2/M phase and also significantly inhibits microtubule polymerization. HDAC-IN-39 exhibits good anticancer effects on HDAC-IN-39 exhibited good anti-cancer effects on drug-resistant cancer cells.
Smiles
N(S(=O)(=O)C1=CC=C(OC)C=C1)C2=C(NCC3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)C=CC=C2
Molecular Formula
C27H26N4O4S
Molecular Weight
502.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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