EGFR/HER2/TS-IN-1
Product Specifications
CAS Number
2444363-11-3
Target
EGFR, Apoptosis, DNA/RNA Synthesis, Others
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair, Apoptosis, Cell Cycle/Checkpoint, JAK/STAT signaling, Others
Bioactivity
EGFR/HER2/TS-IN-1 are EGFR, HER2 and TS (Thymidylate synthase) inhibitors with IC50 values of 0.203, 0.088 and 0.168 μM, respectively, and have the ability to induce apoptosis (MCF7 cell death) .
Smiles
C(#N)C1=C(NC(SCC(NC2=NC=3C(S2)=CC(C)=CC3)=O)=NC1=O)C=4C(=O)C=5C(OC4)=CC=CC5
Molecular Formula
C24H15N5O4S2
Molecular Weight
501.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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