COX-2/sEH-IN-1
Product Specifications
CAS Number
2474977-38-1
Target
Epoxide Hydrolase, Others, COX
Related Pathways
Others, Metabolism, Immunology/Inflammation, Neuroscience
Bioactivity
COX-2/sEH-IN-1 is an orally active dual inhibitor of COX-2 (IC50: 1.24 μM) and sEH (IC50: 0.40 μM), a soluble epoxide hydrolase. COX-2/sEH-IN-1 increases anti-inflammatory effects and significantly reduces cardiovascular risk.
Smiles
N(C(NC1=CC=C(C(F)(F)F)C=C1)=O)C2=NN(C(=C2)C3=CC=CC=C3)C4=CC=C(S(N)(=O)=O)C=C4
Molecular Formula
C23H18F3N5O3S
Molecular Weight
501.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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