SMO-IN-3
Product Specifications
CAS Number
2376914-71-3
Target
Others, Smo, Hedgehog/Smoothened
Related Pathways
Others, Stem Cells, GPCR/G Protein
Bioactivity
SMO-IN-3 is a potent inhibitor of smoothened (SMO) that acts on the hedgehog (Hh) signaling pathway (IC50: 34.09 nM) . SMO-IN-3 inhibits the proliferation of Daoy, a human medulloblastoma cell line, and exhibits anticancer effects.
Smiles
C(=O)(C1=C(NC2=CC=CC=C2)C=CC=C1)N3CCC(N(C(=O)C4=C(C(F)(F)F)C=C(F)C=C4)C)CC3
Molecular Formula
C27H25F4N3O2
Molecular Weight
499.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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