PHA-680632

Product Specifications

CAS Number

398493-79-3

Target

FGFR, PLK, Aurora Kinase

Related Pathways

Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint

Purity

0.9903

Bioactivity

PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.

Smiles

CCc1cccc(CC)c1NC(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1

Molecular Formula

C28H35N7O2

Molecular Weight

501.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

TA812742 100 µL

Lebercilin (LCA5) Mouse Monoclonal Antibody [Clone ID: OTI2D3]

View Details

T4801 5x105 cells / 1 mL

Rat Primary Pulmonary Fibroblasts

View Details

23-481 100 µL

CCDC92 Antibody

View Details

KLN01021 1x 96 Well

GENLISA Canine MIP-1beta (Macrophage Inflammatory Protein 1 Beta) ELISA

View Details

TL502266 1 Kit

Tfdp1 Mouse shRNA Plasmid (Locus ID 21781)

View Details

IC282S-100UG 100 µg

Human CCL7/MCP-3/MARC Alexa Fluor 750 Antibody

View Details