PHA-680632
Product Specifications
CAS Number
398493-79-3
Target
FGFR, PLK, Aurora Kinase
Related Pathways
Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint
Purity
0.9903
Bioactivity
PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
Smiles
CCc1cccc(CC)c1NC(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1
Molecular Formula
C28H35N7O2
Molecular Weight
501.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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