DHFR-IN-1
Product Specifications
CAS Number
2757991-65-2
Target
Antifungal, Others, Antibacterial
Related Pathways
Others, Microbiology/Virology
Bioactivity
DHFR-IN-1 is a selective and potent inhibitor of DHFR (dihydrofolate reductase) (IC50: 40.71 nM) . DHFR-IN-1 exhibited some antifungal activity and good antibacterial activity against Gram-positive and Gram-negative bacteria.DHFR-IN-1 showed good synergy with Levofloxacin with FIC (partial inhibitory concentration index) = 0.249.
Smiles
N(NC1=NC(=CS1)C2=CC=C(O)C=C2)=C3C=4C(NC3=O)=CC=C(S(=O)(=O)N5CCN(C)CC5)C4
Molecular Formula
C22H22N6O4S2
Molecular Weight
498.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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