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RepSox

Product Specifications

CAS Number

446859-33-2

Target

ALK, TGF-beta/Smad

Related Pathways

Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors

Purity

0.9973

Bioactivity

RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM) . RepSox induces adipogenesis in MEFs cells.

Smiles

Cc1cccc(n1)-c1n[nH]cc1-c1ccc2ncccc2n1

Molecular Formula

C17H13N5

Molecular Weight

287.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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