RepSox
Product Specifications
CAS Number
446859-33-2
Target
ALK, TGF-beta/Smad
Related Pathways
Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors
Purity
0.9973
Bioactivity
RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM) . RepSox induces adipogenesis in MEFs cells.
Smiles
Cc1cccc(n1)-c1n[nH]cc1-c1ccc2ncccc2n1
Molecular Formula
C17H13N5
Molecular Weight
287.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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