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Ulecaciclib

Product Specifications

CAS Number

2075750-05-7

Target

Others|||CDK

Related Pathways

Others|||Cell Cycle/Checkpoint

Bioactivity

Ulecaciclib is an orally active, blood-brain barrier-transparent, cell cycle protein-dependent kinase (CDK) inhibitor that exhibits favorable pharmacokinetic profiles, with ki of 0.62 ?M (CDK2/Cyclin A), 3 nM (CDK6/Cyclin D3), 0.2 nM (CDK4/Cyclin D1) and 0.63 ?M (CDK7/Cyclin H) for CDKs. D1) and 0.63 ?M (CDK7/Cyclin H) .

Smiles

CC1=C(SC(NC2CCCC2)=N1)C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F

Molecular Formula

C25H33FN8S

Molecular Weight

496.65

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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