BRD4 Inhibitor-18
Product Specifications
CAS Number
2451219-73-9
Target
Others, Apoptosis, Epigenetic Reader Domain, c-Myc
Related Pathways
Others, Chromatin/Epigenetic, Cell Cycle/Checkpoint, Apoptosis
Bioactivity
BRD4 Inhibitor-18 is a potent BRD4 inhibitor (IC50: 110 nM) with a hydrophobic acetylcyclopentane side chain. BRD4 Inhibitor-18 significantly reduces the proliferation of MV-4-11 cells with high BRD4 levels, inhibits G0/G1 cycle activity, and promotes apoptosis. The inhibition of G0/G1 cycle activity and apoptosis were also observed.
Smiles
CN1C=2C=3C(C(=NC(CC(NC4CCCC4)=O)C2SC1=O)C5=CC=C(Cl)C=C5)=CC(OC)=CC3
Molecular Formula
C26H26ClN3O3S
Molecular Weight
496.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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