BRD4 Inhibitor-18
Product Specifications
CAS Number
2451219-73-9
Target
Others|||Apoptosis|||Epigenetic Reader Domain|||c-Myc
Related Pathways
Others|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||Apoptosis
Bioactivity
BRD4 Inhibitor-18 is a potent BRD4 inhibitor (IC50: 110 nM) with a hydrophobic acetylcyclopentane side chain. BRD4 Inhibitor-18 significantly reduces the proliferation of MV-4-11 cells with high BRD4 levels, inhibits G0/G1 cycle activity, and promotes apoptosis. The inhibition of G0/G1 cycle activity and apoptosis were also observed.
Smiles
CN1C=2C=3C(C(=NC(CC(NC4CCCC4)=O)C2SC1=O)C5=CC=C(Cl)C=C5)=CC(OC)=CC3
Molecular Formula
C26H26ClN3O3S
Molecular Weight
496.02
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![1-Azabicyclo[2.2.1]heptane-4-carboxylic Acid](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
GTR15397991 1 Vial
Lentiviral human DNAJB13 sgRNA gene knockout kit - Lentiviral human DNAJB13 sgRNA gene knockout kit (plasmid)
Ask
View Details MBS1379509-01 0.02 mg (E-Coli)
Recombinant Oryza sativa subsp. japonica Probable histone H2A.7 (Os12g0438000, LOC_Os12g25120)
Ask
View Details 
MBS1379509-02 0.1 mg (E-Coli)
Recombinant Oryza sativa subsp. japonica Probable histone H2A.7 (Os12g0438000, LOC_Os12g25120)
Ask
View Details