ULK1-IN-2
Product Specifications
CAS Number
2497409-01-3
Target
FAK, Autophagy, AMPK, Apoptosis
Related Pathways
Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Autophagy, Cytoskeletal Signaling, Apoptosis, Angiogenesis, PI3K/Akt/mTOR signaling
Purity
0.9997
Bioactivity
ULK1-IN-2 is a potent ULK1 inhibitor with potential anticancer activity, inducing apoptosis while blocking autophagy.ULK1-IN-2 has high cytotoxicity against cancer cells, with an IC50 value of 1.94 μM against A549 cells.ULK1-IN-2 can be used for the study of non-small-cell lung cancer.
Smiles
O(C)C1=C(OC)C=C(NC=2N=C(OC3=C(F)C=C(N(=O)=O)C=C3)C(Br)=CN2)C=C1OC
Molecular Formula
C19H16BrFN4O6
Molecular Weight
495.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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