CCG-273220
Product Specifications
CAS Number
2750414-35-6
Target
Others|||GRK
Related Pathways
GPCR/G Protein|||Others
Bioactivity
CCG-273220 is a covalent inhibitor of G protein-coupled receptor (GPCR) kinase 5 (GRK5) (IC50: 220 nM) .CCG-273220 covalently binds the GRK5 subfamily-specific residue Cys474 and is more selective for GRK5 than GRK2.
Smiles
C[C@@H](NC(=O)c1ccc2NC(=O)\C(=C/c3[nH]c(C)c(NC(=O)CCl)c3C)c2c1)c1ccc(F)cc1
Molecular Formula
C26H24ClFN4O3
Molecular Weight
494.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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