Uplarafenib
Product Specifications
CAS Number
1425485-87-5
Target
Raf
Related Pathways
MAPK
Purity
0.9998
Bioactivity
Uplarafenib (B-Raf IN 10) is a potent BRAF inhibitor with an IC50 of 50-100 nM. B-Raf IN 10 exhibits antitumor activity that may influence cell proliferation and differentiation, making it suitable for studying solid tumors.
Smiles
CCCS(=O)(=O)Nc1cc(F)c(F)c(C(=O)c2ccc3ncc(nc3c2)N2CCOCC2)c1F
Molecular Formula
C22H21F3N4O4S
Molecular Weight
494.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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