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Uplarafenib

Product Specifications

CAS Number

1425485-87-5

Target

Raf

Related Pathways

MAPK

Purity

0.9998

Bioactivity

Uplarafenib (B-Raf IN 10) is a potent BRAF inhibitor with an IC50 of 50-100 nM. B-Raf IN 10 exhibits antitumor activity that may influence cell proliferation and differentiation, making it suitable for studying solid tumors.

Smiles

CCCS(=O)(=O)Nc1cc(F)c(F)c(C(=O)c2ccc3ncc(nc3c2)N2CCOCC2)c1F

Molecular Formula

C22H21F3N4O4S

Molecular Weight

494.49

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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