BCR-ABL-IN-5
Product Specifications
CAS Number
1795736-60-5
Target
Others, Bcr-Abl
Related Pathways
Others, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
BCR-ABL-IN-5 is a Bcr-Abl (Breakpoint cluster region-Abelson) kinase inhibitor that acts on Bcr-AblWT (IC50: 0.014 μM) and Bcr-AblT3151 (IC50: 0.45 μM) and exhibits some anti-proliferative effects on leukemic cells. effect.
Smiles
NC=1C2=C(C=CC=C2NN1)C3=CC=C(C(=O)N4CCN(C(=O)C5=C(Cl)C=C(Cl)C=C5)CC4)C=C3
Molecular Formula
C25H21Cl2N5O2
Molecular Weight
494.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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