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MM-102

Product Specifications

CAS Number

1417329-24-8

Target

TNF|||Interleukin|||Histone Methyltransferase|||NF-?B|||Apoptosis

Related Pathways

Chromatin/Epigenetic|||NF-?B|||Immunology/Inflammation|||Apoptosis

Purity

0.9999

Bioactivity

MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay. MM-102 can also specifically inhibit cell growth and induce apoptosis in leukemia cells carrying MLL1 fusion protein.

Smiles

C(NC(C1=CC=C(F)C=C1)C2=CC=C(F)C=C2)(=O)C3(NC([C@@H](NC(C(NC(C(C)C)=O)(CC)CC)=O)CCCNC(=N)N)=O)CCCC3

Molecular Formula

C35H49F2N7O4

Molecular Weight

669.8

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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