MM-102
Product Specifications
CAS Number
1417329-24-8
Target
TNF|||Interleukin|||Histone Methyltransferase|||NF-?B|||Apoptosis
Related Pathways
Chromatin/Epigenetic|||NF-?B|||Immunology/Inflammation|||Apoptosis
Purity
0.9999
Bioactivity
MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay. MM-102 can also specifically inhibit cell growth and induce apoptosis in leukemia cells carrying MLL1 fusion protein.
Smiles
C(NC(C1=CC=C(F)C=C1)C2=CC=C(F)C=C2)(=O)C3(NC([C@@H](NC(C(NC(C(C)C)=O)(CC)CC)=O)CCCNC(=N)N)=O)CCCC3
Molecular Formula
C35H49F2N7O4
Molecular Weight
669.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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