IRAK4-IN-19
Product Specifications
Target
Others, IRAK
Related Pathways
NF-κB, Others, Immunology/Inflammation
Bioactivity
IRAK4-IN-19 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) with an IC50 of 4.3 nM. It inhibits LPS-induced IL23 production in THP and DC cells and suppresses arthritis development in arthritic model rats. IRAK4-IN-19 can be used to study arthritic diseases.
Molecular Formula
C25H26F2N8O
Molecular Weight
492.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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