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IRAK4-IN-19

Product Specifications

Target

Others, IRAK

Related Pathways

NF-κB, Others, Immunology/Inflammation

Bioactivity

IRAK4-IN-19 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) with an IC50 of 4.3 nM. It inhibits LPS-induced IL23 production in THP and DC cells and suppresses arthritis development in arthritic model rats. IRAK4-IN-19 can be used to study arthritic diseases.

Molecular Formula

C25H26F2N8O

Molecular Weight

492.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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