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EGFR-IN-34

Product Specifications

Target

Others, EGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Others, JAK/STAT signaling

Bioactivity

EGFR-IN-34 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-34 exhibits potential for research in EGFR mutation-related diseases.

Smiles

NC1=C(C(C2=CC=C(OCC3=NC=CC=C3)C(Cl)=C2)=CN4[C@H]5CN(C(C=C)=O)CCC5)C4NC=N1

Molecular Formula

C26H27ClN6O2

Molecular Weight

490.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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