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P-gp/BCRP-IN-1

Product Specifications

CAS Number

2764596-06-5

Target

BCRP, Others

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

P-gp/BCRP-IN-1 (compound 19) is a relatively safe, orally active, and efficient inhibitor of the efflux transporters P-gp and BCRP, which reverses resistance and enhances the oral bioavailability of Paclitaxel (PTX) [1].

Smiles

C(NC1=CC=C(CCN2CCOCC2)C=C1)(=O)C=3C=4C(C(=O)N(N3)C5=CC=C(Cl)C=C5)=CC=CC4

Molecular Formula

C27H25ClN4O3

Molecular Weight

488.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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