P-gp/BCRP-IN-1
Product Specifications
CAS Number
2764596-06-5
Target
BCRP, Others
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
P-gp/BCRP-IN-1 (compound 19) is a relatively safe, orally active, and efficient inhibitor of the efflux transporters P-gp and BCRP, which reverses resistance and enhances the oral bioavailability of Paclitaxel (PTX) [1].
Smiles
C(NC1=CC=C(CCN2CCOCC2)C=C1)(=O)C=3C=4C(C(=O)N(N3)C5=CC=C(Cl)C=C5)=CC=CC4
Molecular Formula
C27H25ClN4O3
Molecular Weight
488.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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