EGFR-IN-36
Product Specifications
CAS Number
2711105-54-1
Target
Others, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Others, Angiogenesis
Bioactivity
EGFR-IN-36 is a potent inhibitor of EGFR, acting on EGFR (WT) (IC50: 19.09 nM), HER2 (WT) (IC50: 120.01 nM), and HER2 (A775_G776insYVMA) (IC50: 2.35 nM) . EGFR-IN-36 exhibits potential for studying wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.
Smiles
NC=1C2=C(C=C(N2N=CN1)C3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4
Molecular Formula
C26H25ClN6O2
Molecular Weight
488.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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