EGFR-IN-33
Product Specifications
CAS Number
2711105-59-6
Target
EGFR, Others
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Others
Bioactivity
EGFR-IN-33, an acrylamide derivative, is a low-toxicity antitumor agent and a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-33 exhibits potential for the study of EGFR mutation-related diseases.
Smiles
NC1=C2N(C=C(C2=NC=N1)C3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4
Molecular Formula
C26H25ClN6O2
Molecular Weight
488.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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