NTU281
Product Specifications
CAS Number
815619-12-6
Target
Others, Glutaminase, Apoptosis
Related Pathways
Proteases/Proteasome, Others, Apoptosis
Bioactivity
NTU281 is a potent inhibitor of transglutaminase-2 that reduces the elevation of serum creatinine and proteinuria in diabetic rats and decreases glomerular type I collagen accumulation, Hic-5 and α-SMA expression, as well as apoptosis, and can be used in studies of diabetes-induced glomerulosclerosis.
Smiles
[C@H](CC1=CC=CC=C1)(C(N[C@@H](CCC(C[S+](C)C)=O)C(O)=O)=O)NC(OCC2=CC=CC=C2)=O
Molecular Formula
C25H31N2O6S
Molecular Weight
487.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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