(E/Z) -BIX02188
Product Specifications
CAS Number
1094614-84-2
Target
TGF-beta/Smad, ERK, MEK, Others
Related Pathways
MAPK, Others, Stem Cells
Purity
0.9921
Bioactivity
BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1/2, JNK2, and ERK2.
Smiles
CN(C)Cc1cccc(NC(=C2C(=O)Nc3cc(ccc23)C(N)=O)c2ccccc2)c1
Molecular Formula
C25H24N4O2
Molecular Weight
412.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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