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T-2513 hydrochloride

Product Specifications

CAS Number

187793-52-8

Target

Others, DNA/RNA Synthesis, Topoisomerase

Related Pathways

Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

T-2513 hydrochloride, a selective inhibitor of topoisomerase I, covalently binds to the topoisomerase I-DNA complex, stabilizing it and inhibiting DNA replication and RNA synthesis, ultimately leading to cell death.

Smiles

Cl.CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OCCCN)cc12

Molecular Formula

C25H28ClN3O5

Molecular Weight

485.96

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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