T-2513 hydrochloride
Product Specifications
CAS Number
187793-52-8
Target
Others, DNA/RNA Synthesis, Topoisomerase
Related Pathways
Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
T-2513 hydrochloride, a selective inhibitor of topoisomerase I, covalently binds to the topoisomerase I-DNA complex, stabilizing it and inhibiting DNA replication and RNA synthesis, ultimately leading to cell death.
Smiles
Cl.CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OCCCN)cc12
Molecular Formula
C25H28ClN3O5
Molecular Weight
485.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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