What is the catalog number for SR12418?

The catalog number for SR12418 is T63206.

What sizes are available for SR12418?

SR12418 is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg.

How many pack sizes does SR12418 come in?

SR12418 is available in 6 different pack sizes.

SR12418 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SR12418?

SR12418 is manufactured by Molfinity.

What is the estimated delivery time for SR12418?

Estimated delivery time for SR12418 is approximately 10 business day(s), depending on your location.

SR12418

Product Specifications

CAS Number

1801185-08-9

Target

Autophagy, REV-ERB, IL Receptor

Related Pathways

Immunology/Inflammation, Autophagy, Metabolism

Purity

0.9996

Bioactivity

SR12418 is a specific synthetic ligand for REV-ERB, demonstrating binding affinity for both REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. SR12418 inhibits IL-17A expression in EL4 cells and suppresses TH17 cell differentiation, making it suitable for studies on experimental autoimmune encephalomyelitis (EAE) and colitis.