EGFR/BRAF-IN-1
Product Specifications
Target
Others, EGFR, Raf
Related Pathways
Angiogenesis, JAK/STAT signaling, Others, MAPK, Tyrosine Kinase/Adaptors
Bioactivity
EGFR/BRAF-IN-1, a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potent inhibitor of EGFR/BRAF, inhibiting BRAFV600E (IC50:45 nM) and cancer cell proliferation (GI50=35 nM), with good antioxidant effect.
Molecular Formula
C26H28ClN3O4
Molecular Weight
481.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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