EGFR/BRAF-IN-1

Product Specifications

Target

Others|||EGFR|||Raf

Related Pathways

Angiogenesis|||JAK/STAT signaling|||Others|||MAPK|||Tyrosine Kinase/Adaptors

Bioactivity

EGFR/BRAF-IN-1, a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potent inhibitor of EGFR/BRAF, inhibiting BRAFV600E (IC50:45 nM) and cancer cell proliferation (GI50=35 nM), with good antioxidant effect.

Molecular Formula

C26H28ClN3O4

Molecular Weight

481.97

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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