RET-IN-9
Product Specifications
CAS Number
2649418-11-9
Target
Others|||c-RET
Related Pathways
Tyrosine Kinase/Adaptors|||Apoptosis|||Others
Bioactivity
RET-IN-9 is a potent inhibitor of RET, a single-channel transmembrane receptor tyrosine kinase involved in kidney and enteric nervous system development, as well as in maintaining homeostasis in the nervous, endocrine, hematopoietic, and male reproductive systems. RET-IN-9 is potentially useful in studying RET-related diseases, including non-small cell lung cancer and medullary thyroid cancer.
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C(#N)C1=C2C(=CC(NCC)=CN2N=C1)C=3C=NC(=CN3)N4CC5N(CC=6C=CC(OC)=NC6)C(C4)C5
Molecular Formula
C26H27N9O
Molecular Weight
481.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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