AZ 628
Product Specifications
CAS Number
878739-06-1
Target
Raf, Apoptosis
Related Pathways
MAPK, Apoptosis
Purity
0.995
Bioactivity
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.
Smiles
Cc1ccc(NC(=O)c2cccc(c2)C(C)(C)C#N)cc1Nc1ccc2ncn(C)c(=O)c2c1
Molecular Formula
C27H25N5O2
Molecular Weight
451.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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