AZ 628

Product Specifications

CAS Number

878739-06-1

Target

Raf|||Apoptosis

Related Pathways

MAPK|||Apoptosis

Purity

0.995

Bioactivity

AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.

Smiles

Cc1ccc(NC(=O)c2cccc(c2)C(C)(C)C#N)cc1Nc1ccc2ncn(C)c(=O)c2c1

Molecular Formula

C27H25N5O2

Molecular Weight

451.52

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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