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EGFR-IN-39

Product Specifications

CAS Number

2711105-48-3

Target

Others, EGFR

Related Pathways

JAK/STAT signaling, Others, Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

EGFR-IN-39, an acrylamide derivative, is a potent inhibitor of EGFR. EGFR-IN-39 is an antitumor agent with low toxicity and side effects. Among them, the overexpression and mutation of epidermal growth factor receptor (EGFR) have been clearly confirmed to cause uncontrollable cell growth, and are related to the progression of most cancer diseases, especially NSCLC. EGFR-IN-33 has the potential to study EGFR mutation-related diseases.

Smiles

C(N)(=O)C=1N(N=C(C1N)C2CN(C(C=C)=O)CCC2)C3=CC(Cl)=C(OCC4=CC=CC=N4)C=C3

Molecular Formula

C24H25ClN6O3

Molecular Weight

480.95

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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