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LX-039

Product Specifications

CAS Number

2135341-09-0

Target

Estrogen Receptor/ERR, Others

Related Pathways

Endocrinology/Hormones, Others

Bioactivity

LX-039 is a potent, selective, orally active estrogen receptor degrader (EC50: 2.99 nM) with antitumor effects.LX-039 has indole C-3 chloride atoms.LX-039 has good pharmacokinetic properties in mice, low clearance, high blood levels and oral exposure.

Smiles

C(=C(CC)C1=C(Cl)C=C(F)C=C1)(C2=C(Cl)C=3C(N2)=CC=CC3)C4=CC=C(C=CC(O)=O)C=C4

Molecular Formula

C27H20Cl2FNO2

Molecular Weight

480.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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