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EGFR/HER2/CDK9-IN-3

Product Specifications

CAS Number

422276-47-9

Target

CDK|||Others|||EGFR

Related Pathways

JAK/STAT signaling|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||Others|||Angiogenesis

Bioactivity

EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR (IC50:191.08 nM), HER2 (IC50:132.65 nM), and CDK9 (IC50:113.98 nM), demonstrating significant anti-tumor effects.

Smiles

C(CC1=CC=C(S(N)(=O)=O)C=C1)N2C(SCC(=O)C3=CC=CC=C3)=NC=4C(C2=O)=CC=CC4

Molecular Formula

C24H21N3O4S2

Molecular Weight

479.57

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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