HCAIX-IN-10
Product Specifications
CAS Number
2497504-72-8
Target
Others, Carbonic Anhydrase
Related Pathways
Metabolism, Others
Bioactivity
HCAIX-IN-10 (Compound 6i) is a selective inhibitor of carbonic anhydrase IX and XII, targeting hCA IX (Ki: 61.5 nM) and hCA XII (Ki: 586.8 nM) . hCA IX and hCA XII are transmembrane isoforms of carbonic anhydrase and serve as biomarkers for certain types of tumors, with hCA XII also playing a role in maintaining acid-base homeostasis in both normal and tumor cells.
Smiles
O=C1C(C=2C(=CN(N2)C3=CC=CC=C3)C4N(C(=O)CS4)C5=CC(C)=CC=C5)=CC=6C(O1)=CC=CC6
Molecular Formula
C28H21N3O3S
Molecular Weight
479.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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